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KMID : 1103920080140040519
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Korean Journal of Hepatology
2008 Volume.14 No. 4 p.519 ~ p.524
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Treatment with pegylated interferon and ribavirin in a patient with fibrosing cholestatic hepatitis due to recurrent hepatitis C after liver transplantation
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Kim Byung-Kook
Kwon So-Young
Lee Chang-Hong
Han Hye-Seung
Chang Seong-Hwan
Ko Soon-Young
Choe Won-Hyeok
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Abstract
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Fibrosing cholestatic hepatitis (FCH) is the most devastating manifestation of recurrent hepatitis C in transplant recipients with hepatitis C virus (HCV), possibly leading to death or retransplantation. Although FCH was first described as a complication of hepatitis B, this manifestation has been well documented in association with HCV in the setting of liver transplantation, bone marrow transplantation, heart transplantation, and end-stage human immunodeficiency virus infection. We report the clinical course and antiviral response in a patient with FCH due to recurrent hepatitis C after cadaveric liver transplantation who was treated with pegylated interferon α-2a and ribavirin.
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KEYWORD
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Hepatitis C, Liver Transplantation, Cholestasis, Fibrosis
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